Hepatocellular Carcinoma Understanding Advanced Liver Cancer What is unresectable or advanced liver cancer? Liver cancer develops when liver cells undergo a change that causes them to multiply uncontrollably, forming a lump or tumor. When liver cancer has grown too large, spread to other parts of the liver or spread to other parts of the body, or cannot be surgically excised, it is called unresectable or advanced liver cancer. Your healthcare team has prescribed a combination of 2 immunotherapies because they believe it will help treat your type of liver cancer. Although there are different types of liver cancer, Hepatocellular Carcinoma (HCC) is the most common. CC-16877 / MAY 2028.