Mantle Cell Lymphoma (MCL)

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Mantle Cell Lymphoma is a type of cancer in the lymphatic system caused by an uncontrolled growth of B lymphocytes found in the follicular mantle area of ​​the lymph nodes. MCL represents 6% of Non-Hodgkin Lymphomas. 

The increase in malignant or abnormal B lymphocytes in the bone marrow leaves little room for red blood cells or platelets, therefore, they decrease in number. This leads to the appearance of symptoms such as fatigue or increased infections.

B cells can accumulate in the lymph nodes or in organs such as the spleen, liver, intestines, among others; this is perceived as an inflammation of the lymph nodes or the organ where they are located.

Mantle cell lymphoma signs and symptoms


National Comprehensive Cancer Network Guidelines for Patients: Mantle Cell Lymphoma, NCCC Non Hodgkin Lymphoma Series, 2017.

Janssen-Cilag. Linfoma de Células del Manto, 2018. Disponible en:

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